Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 15/20 | 1.00 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 2/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836945 | 0.89 | NPY5R (1.00) | NPY5RMAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL6837065 | 0.87 | NPY5R (1.00) | NPY5R | |
| SCHEMBL6835533 | 0.82 | NPY5R (1.00) | NPY5RMAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL6835590 | 0.82 | NPY5R (1.00) | NPY5R | |
| SCHEMBL6835180 | 0.81 | NPY5R (0.69) | NPY5RMAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL11862464 | 0.74 | NPY5R (0.59) | NPY5RTEK | |
| SCHEMBL6831681 | 0.68 | NPY5R (0.52) | NPY5R | |
| SCHEMBL4231016 | 0.68 | CYP19A1 (0.85) | — | |
| SCHEMBL4231019 | 0.68 | CYP19A1 (0.85) | — | |
| SCHEMBL4231022 | 0.68 | CYP19A1 (0.85) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | H1-0, H1-5, H1-3 | NPY5R 983/4885MAPK13 4148/4885RAF1 3612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.