Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 7/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839750 | 1.00 | KDM1A (0.52) | KDM1AMAOBF10HRH3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6835549 | 0.99 | KDM1A (0.51) | KDM1AMAOBF10HRH3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6835548 | 0.99 | KDM1A (0.51) | KDM1AMAOBF10HRH3SMN1; SMN2 | |
| SCHEMBL6840553 | 0.91 | KDM1A (0.55) | KDM1AMAOBF10HRH3SMN1; SMN2 | |
| SCHEMBL6840555 | 0.91 | KDM1A (0.55) | KDM1AMAOBF10HRH3SMN1; SMN2 | |
| SCHEMBL6835595 | 0.86 | KDM1A (0.59) | KDM1AMAOBF10HRH3SMN1; SMN2 | |
| SCHEMBL6842235 | 0.86 | KDM1A (0.59) | KDM1AMAOBF10HRH3SMN1; SMN2 | |
| SCHEMBL6842236 | 0.86 | KDM1A (0.59) | KDM1AMAOBF10HRH3SMN1; SMN2 | |
| SCHEMBL6842273 | 0.84 | KDM1A (0.59) | KDM1AMAOBF10HRH3SMN1; SMN2 | |
| SCHEMBL5164898 | 0.78 | SMN1; SMN2 (0.52) | KDM1AMAOBF10SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082563-A1 | Phenyl derivatives 3 | MERCK PATENT GMBH (DE) | 2004-04-29 | — | — | US | claimed |
| US-20040082563-A1 | Phenyl derivatives 3 | MERCK PATENT GMBH (DE) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082563-A1 | Phenyl derivatives 3 | F2, F11, F12 | KDM1A 452/4885MAOB 435/4885F10 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.