Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 18/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6833117 | 0.95 | MMP13 (0.71) | MMP13 | |
| SCHEMBL6835785 | 0.88 | MMP13 (0.83) | MMP13 | |
| SCHEMBL6834151 | 0.87 | MMP13 (1.00) | MMP13 | |
| SCHEMBL6833119 | 0.87 | MMP13 (0.59) | MMP13 | |
| SCHEMBL5697007 | 0.86 | MMP13 (1.00) | MMP13 | |
| SCHEMBL6833710 | 0.86 | MMP13 (1.00) | MMP13 | |
| Trifluoroacetic Acid SCHEMBL6833136 | 0.83 | MMP13 (0.76) | MMP13 | |
| Trifluoroacetic Acid SCHEMBL6830140 | 0.83 | MMP13 (0.90) | MMP13 | |
| SCHEMBL5697090 | 0.82 | MMP13 (0.73) | MMP13 | |
| Trifluoroacetic Acid SCHEMBL6830520 | 0.81 | MMP13 (0.90) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747147-B2 | INHIBITORS OF TYPE-13 MATRIX METTALOPROTEASE. RHEUMATOID ARTHRITIS OR OSTEOARTHRITIS, AS WELL AS CERTAIN PROLIFERATIVE CONDITIONS SUCH AS CANCERS, PARTICULARLY HUMAN BREAST CANCER | WARNER-LAMBERT COMPANY | 2004-06-08 | — | — | US | claimed |