Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368306 | 0.87 | ALDH1A1 (0.51) | KMT2AMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL1848132 | 0.85 | KDM4E (0.49) | KMT2AMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL9368107 | 0.81 | ALDH1A1 (0.46) | KMT2AMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL2682770 | 0.79 | MAPT (0.48) | KMT2AMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL1844332 | 0.79 | SMN1; SMN2 (0.57) | KMT2AMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL31398801 | 0.78 | MAPT (0.47) | KMT2AMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL2761037 | 0.77 | CA1 (0.39) | KMT2AMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL2809243 | 0.77 | MAPT (0.56) | KMT2AMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL15210919 | 0.77 | MAPT (0.56) | KMT2AMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL1086028 | 0.77 | KMT2A (0.56) | KMT2AMAPTHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107954976-B | A method of synthesis 3,4- dimethoxy-thiophene | 贝利化学（张家港）有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-107954976-A | A kind of method of synthesis 3,4- dimethoxy-thiophenes | 贝利化学（张家港）有限公司 | 2018-04-24 | — | — | CN | claimed |
| CN-110183465-A | The preparation method of (2,3- dihydro-thiophene simultaneously [3,4-B] [1,4] dioxane hex- 2- yl) methanol | 福建博鸿新能源科技有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-107954976-B | A method of synthesis 3,4- dimethoxy-thiophene | 贝利化学（张家港）有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-107954976-B | A method of synthesis 3,4- dimethoxy-thiophene | 贝利化学（张家港）有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-107954976-A | A kind of method of synthesis 3,4- dimethoxy-thiophenes | 贝利化学（张家港）有限公司 | 2018-04-24 | — | — | CN | disclosed |
| CN-1644580-A | Position fixable polymerized precursor of polythiazole monomer and its synthesis | XU LIANGHENG (CN) | 2005-07-27 | — | — | CN | disclosed |
| US-6750354-B2 | ALKYLATION OF 3,4- DIHYDROXYTHIOPHENE-2, 5-DICARBOXYLIC ESTERS OR THEIR ALKALI METAL OR ALKALINE EARTH METAL SALTS WITH ALKYLATING AGENTS IN A POLAR DILUENT IN THE PRESENCE OF QUATERNARY ONIUM SALTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | disclosed |
| US-20030097007-A1 | Process for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | H. C. STARCK GMBH (DE) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097007-A1 | Process for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | DIMT1, AS3MT, DDT | KMT2A 195/4885MAPT 1684/4885HSD17B10 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.