SCHEMBL6836241

SCHEMBL6836241

O=C(Cl)C(O)C(O)C(=O)Cl

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
HIF1A Q16665 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13997338 0.84 TSHR (0.35) TSHRLMNA
SCHEMBL9557333 0.76
Acetic Acid SCHEMBL20853828 0.73 FFAR3 (0.41) TSHRLMNA
SCHEMBL10045830 0.73
SCHEMBL859262 0.70
SCHEMBL29699725 0.70
SCHEMBL27220967 0.70
SCHEMBL18072550 0.70
SCHEMBL27693189 0.70
SCHEMBL1742191 0.67 LMNA (0.33) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103250737-A Low corrosion oxidation potential sterilization water and preparation method thereof SHAO PENGFEI 2013-08-21 CN disclosed
US-6752929-B1 SEPARATING THE CIS AND THE TRANS DIASTEREOMERS OF THE 2',3'-DIDEOXY-5-FLUORO-3'THIOCYTADINE DERIVATIVE BY SIMULATED MOVING BED CHROMATOGRAPHY TO OBTAIN AT LEAST ONE OF THE DIASTEREOMERS JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. 2004-06-22 US disclosed
US-6541631-B1 Forming a solution containing first and second enantiomer of cis-(5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathi olan-2-yl)methyl butanoate, separating first and second enantiomer by simulated moving bed chromatography PHARMA-ECO LABORATORIES, INC. 2003-04-01 US disclosed
EP-1180104-B1 METHODS OF SEPARATING FTC ISOMERS AND DERIVATIVES THEREOF JOHNSON MATTHEY PHARMACEUTICAL (US) 2003-03-26 EP disclosed
EP-1180104-A1 METHODS OF SEPARATING FTC ISOMERS AND DERIVATIVES THEREOF Pharm-Eco Laboratories Inc. (US) 2002-02-20 EP disclosed
WO-2000071539-A1 METHODS OF SEPARATING FTC ISOMERS AND DERIVATIVES THEREOF PHARM-ECO LABORATORIES INC. (US) 2000-11-30 WO disclosed
EP-0735056-B1 Catalyst for the polymerization of olefines and processes for the polymerization of olefines using the same TONEN CORP (JP) 1998-06-10 EP disclosed
US-5747595-A TRIALKOXYALKYLSILANE TONEN CORPORATION (JP) 1998-05-05 US disclosed
EP-0735056-A1 Catalyst for the polymerization of olefines and processes for the polymerization of olefines using the same Tonen Corporation (JP) 1996-10-02 EP disclosed
US-5061667-A REDUCED POWDERING OF POLYMER DURING POLYMERIZATION TOG NENRYO KOGYO KK (TONEN CORPORATION) (JP) 1991-10-29 US disclosed
EP-0193281-A2 Catalyst component for olefin polymerization TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-09-03 EP disclosed
EP-0173472-A2 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-03-05 EP disclosed
EP-0173470-A2 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-03-05 EP disclosed
EP-0171200-A2 Catalyst component for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-02-12 EP disclosed
US-4565798-A COORDINATION CATALYSTS, TITANIUM, MAGNESIUM, SILICON COMPOUND TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-01-21 US disclosed
EP-0157472-A1 Process for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-10-09 EP disclosed
EP-0156512-A1 Process for preparing catalyst component for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-10-02 EP disclosed
EP-0147053-A1 A catalyst and a process for polymerization of olefins Tonen Corporation (JP) 1985-07-03 EP disclosed
EP-0145368-A2 Process for producing propylene block copolymers TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-06-19 EP disclosed
US-4396605-A Bis-thymosine α-1 compounds MAX-PLANCK GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1983-08-02 US disclosed