Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068626 | 0.89 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL7068936 | 0.86 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL4829047 | 0.85 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL7132041 | 0.85 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL5802846 | 0.83 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL6835547 | 0.81 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL1398707 | 0.77 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL1398620 | 0.77 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL1398677 | 0.77 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL6832457 | 0.77 | HCRTR1 (0.43) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441729-A1 | PIPERAZINE BIS-AMIDE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF THE OREXIN RECEPTOR | SMITHKLINE BEECHAM PLC (GB) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003041711-A1 | PIPERAZINE BIS-AMIDE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF THE OREXIN RECEPTOR | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-05-22 | — | — | WO | disclosed |