Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802204 | 0.89 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL6836698 | 0.83 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL5822757 | 0.81 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL1398620 | 0.80 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL1398677 | 0.80 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL1398707 | 0.80 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL4002978 | 0.79 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL4003868 | 0.79 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| Sb-649868 SCHEMBL8045969 | 0.78 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| Sb-649868 SCHEMBL29424764 | 0.78 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006081522-A2 | MODULATION OF NMDA RECEPTOR CURRENTS VIA OREXIN RECEPTOR AND/OR CRF RECEPTOR | THE REGENTS OF THE UNVERSITY OF CALIFORNIA (US) | 2006-08-03 | — | — | WO | disclosed |
| EP-1289955-A1 | PIPERIDINES FOR USE AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096302-A1 | PIPERIDINES FOR USE AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-12-20 | — | — | WO | disclosed |