Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177139 | 0.79 | DRD3 (0.44) | ALDH1A1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL6050329 | 0.75 | NR1H2 (0.46) | ALDH1A1TDP1CDC25ACA12CA9 | |
| SCHEMBL6329301 | 0.75 | DRD3 (0.43) | ALDH1A1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL8331683 | 0.74 | NR1H2 (0.49) | ALDH1A1CDC25ACA12CA9 | |
| SCHEMBL8332447 | 0.74 | NR1H2 (0.49) | ALDH1A1CDC25ACA12CA9 | |
| SCHEMBL8328628 | 0.74 | NR1H2 (0.49) | ALDH1A1CDC25ACA12CA9 | |
| SCHEMBL6214680 | 0.74 | DRD3 (0.40) | ALDH1A1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL27473685 | 0.73 | ALDH1A1 (0.40) | ALDH1A1CASP3RAB9ASMN1; SMN2GAA | |
| SCHEMBL1307183 | 0.72 | NPC1 (0.62) | CASP3NPC1RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL17077234 | 0.71 | HEXA (0.45) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043029-A1 | Novel antibodies reactive with human carcinomas | BRISTOL-MYERS SQUIBB COMPANY | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043029-A1 | Novel antibodies reactive with human carcinomas | LY96, FUCA1, FUCA2 | ALDH1A1 4306/4885CASP3 4090/4885NPC1 3473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.