SCHEMBL6837508

SCHEMBL6837508

CO[C@@H](COP(=O)(O)O)[C@H](O)CO

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGD P52209 4/20 0.44
MPI P34949 1/20 0.44
PGK1 P00558 1/20 0.42
PGK2 P07205 1/20 0.42
LPAR5 Q9H1C0 1/20 0.37
ENPP2 Q13822 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27622621 0.85 PGD (0.48) PGDMPIPGK1PGK2LPAR5
SCHEMBL715384 0.85 PGD (0.48) PGDMPIPGK1PGK2LPAR5
SCHEMBL3744531 0.82 PGD (0.46) PGDMPIPGK1PGK2LPAR5
SCHEMBL18341438 0.77 PGD (0.57) PGDMPIPGK1PGK2LPAR5
SCHEMBL20455444 0.77 PGD (0.57) PGDMPIPGK1PGK2LPAR5
E968 SCHEMBL18341348 0.77 PGD (0.57) PGDMPIPGK1PGK2LPAR5
E968 SCHEMBL18341349 0.77 PGD (0.57) PGDMPIPGK1PGK2LPAR5
SCHEMBL5081076 0.77 PGD (0.57) PGDMPIPGK1PGK2LPAR5
SCHEMBL14941155 0.77 PGD (0.57) PGDMPIPGK1PGK2LPAR5
SCHEMBL3744708 0.77 PGD (0.57) PGDMPIPGK1PGK2LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115786155-A Saccharomyces cerevisiae for producing squalene as well as construction method and application thereof 万华化学集团股份有限公司 2023-03-14 CN disclosed
US-20040010815-A1 Identification and characterization of plant genes SYNGENTA PARTICIPATIONS AG (CH) 2004-01-15 US disclosed
WO-2003103668-A1 PYRIDIN-2-ONE AND QUINOLIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS ANTIBACTERIALS KARO BIO AB (SE) 2003-12-18 WO disclosed
EP-1151079-A4 1-DEOXY-D-XYLULOSE-5-PHOSPHATE REDUCTOISOMERASES, AND METHODS OF USE UNIV WASHINGTON (US) 2003-05-02 EP disclosed
US-20010046694-A1 1-deoxy-D-xylulose-5-phosphate reductoisomerases, and methods of use WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION 2001-11-29 US disclosed
EP-1151079-A1 1-DEOXY-D-XYLULOSE-5-PHOSPHATE REDUCTOISOMERASES, AND METHODS OF USE WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 2001-11-07 EP disclosed
US-6281017-B1 A NUCLEIC ACID MOLECULE; INVOLVED IN THE PRODUCUTION OF INTERMEDIATES TO ISOPRENOIDS WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION 2001-08-28 US disclosed
WO-2000046346-A1 1-DEOXY-D-XYLULOSE-5-PHOSPHATE REDUCTOISOMERASES, AND METHODS OF USE WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 2000-08-10 WO disclosed