Phthalic Acid

Phthalic Acid

SCHEMBL6837519

Cc1nc(N)nc(N)n1.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
ALOX15 P16050 1/20 0.54
GABRP O00591 1/20 0.47
GABRD O14764 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRB1 P18505 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
GABRA4 P48169 1/20 0.47
GABRE P78334 1/20 0.47
GABRA6 Q16445 1/20 0.47
GABRG1 Q8N1C3 1/20 0.47
GABRG3 Q99928 1/20 0.47
GABRQ Q9UN88 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
MYC P01106 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL29234747 0.90 ALDH1A1 (0.67) ALDH1A1ALOX15GABRPGABRDGABRA1
Phthalic Acid SCHEMBL581001 0.90 ALDH1A1 (0.67) ALDH1A1ALOX15GABRPGABRDGABRA1
Phthalic Acid SCHEMBL3640036 0.83 ALDH1A1 (0.52) ALDH1A1ALOX15GABRPGABRDGABRA1
Benzoguanamine SCHEMBL6837505 0.79 ADORA2A (0.70) ALDH1A1ALOX15AKR1C3HPGDNPC1
Salicylic Acid SCHEMBL28232195 0.78 ALDH1A1 (0.72) ALDH1A1ALOX15SMN1; SMN2NR4A1IDO1
Phenol SCHEMBL5507454 0.77 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2CYP1A2HPGDNUDT1
Oxalic Acid SCHEMBL11523305 0.77 CYP1A2 (0.44) ALDH1A1GABRPGABRDGABRA1GABRB1
Acetic Acid SCHEMBL1937495 0.77 CYP1A2 (0.44) ALDH1A1GABRPGABRDGABRA1GABRB1
Phthalic Acid SCHEMBL7722102 0.76 ALDH1A1 (0.82) ALDH1A1ALOX15SMN1; SMN2MYCAKR1C3
Phthalic Acid SCHEMBL4758326 0.76 ALDH1A1 (0.82) ALDH1A1ALOX15SMN1; SMN2MYCAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756166-B2 ACTIVE ENERGY RAY-CURABLE RESIN HAVING AT LEAST TWO UNSATURATED BONDS; ACID SALT OF N-SUBSTITUTED MELAMINE OR GUANAMINE COMPOUND; PHOTOINITIATOR; DILUENT; AND THERMOSETTING COMPOUND. TAMURAKAKEN CORPORATION (JP) 2004-06-29 US disclosed
US-20030068567-A1 Photosensitive resin composition and printed wiring board TAMURA KAKEN CORPORATION (JP) 2003-04-10 US disclosed