Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 16/20 | 0.55 |
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833282 | 0.89 | PDE4D (0.52) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6833327 | 0.87 | PDE4D (0.54) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5722957 | 0.86 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5722910 | 0.79 | PDE4D (0.58) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5722857 | 0.78 | SGMS2 (0.42) | — | |
| SCHEMBL5722841 | 0.76 | SGMS2 (0.48) | — | |
| SCHEMBL885179 | 0.74 | PDE4D (0.82) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5723061 | 0.74 | PDE4D (0.50) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6833350 | 0.73 | PDE4D (0.58) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7141568 | 0.73 | PDE4D (0.49) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716987-B1 | PHOSPHODIESTERASE IV INHIBITORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-04-06 | — | — | US | disclosed |
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |