Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838012 | 1.00 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL30518149 | 1.00 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL6837651 | 1.00 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL11136769 | 1.00 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL2361182 | 1.00 | CYP1A2 (0.57) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL3294321 | 0.98 | CYP2D6 (0.55) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL2579537 | 0.90 | CYP2D6 (0.48) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL11645727 | 0.83 | CHRM2 (0.56) | CYP1A2CYP2C19CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL9273193 | 0.83 | CYP2D6 (0.38) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL29078136 | 0.83 | CHRM2 (0.56) | CYP1A2CYP2C19CYP2D6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992537-B1 | Oil extended rubber and rubber composition | JSR CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| EP-1000970-B1 | Polymodal conjugated diolefin vinyl aromate rubber composition | JSR CORP (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-6362272-B1 | CONJUGATED DIOLEFIN AND AROMATIC VINYL COPOLYMER | JSR CORPORATION (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6344518-B1 | Conjugated diolefin copolymer rubber and rubber composition | JSR CORPORATION (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-1000970-A1 | Polymodal conjugated diolefin vinyl aromate rubber composition | JSR Corporation (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0992537-A1 | Oil extended rubber and rubber composition | JSR Corporation (JP) | 2000-04-12 | — | — | EP | disclosed |