SCHEMBL6837847

SCHEMBL6837847

NC1(NC(=O)C2CCCC2)CCNCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
POLB P06746 1/20 0.39
PADI1 Q9ULC6 1/20 0.36
PADI4 Q9UM07 1/20 0.36
KDM4E B2RXH2 3/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
ATM Q13315 1/20 0.35
CYP2D6 P10635 1/20 0.35
HPGD P15428 2/20 0.35
PTPN1 P18031 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
CCR2 P41597 1/20 0.35
TSHR P16473 1/20 0.35
EPHX1 P07099 2/20 0.34
HSD17B10 Q99714 2/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28737430 0.85 POLB (0.36) POLBKDM4EKMT2AHDAC3HDAC1
SCHEMBL782010 0.72 KDM4E (0.41) KDM4EKMT2ACYP2D6HDAC1TSHR
SCHEMBL7313301 0.72 SSTR4 (0.56) HPGDHDAC3HDAC1HDAC2ALDH1A1
Hydrochloric Acid SCHEMBL7750679 0.71 SSTR4 (0.55) HPGDHDAC3HDAC1HDAC2ALDH1A1
SCHEMBL20224884 0.70 POLB (0.46) POLBPADI1PADI4KDM4EKMT2A
SCHEMBL7314168 0.70 SSTR4 (0.54) HPGDALDH1A1LMNA
Hydrochloric Acid SCHEMBL7751607 0.69 SSTR4 (0.53) HPGDALDH1A1LMNA
Hydrochloric Acid SCHEMBL17848602 0.69 POLB (0.44) POLBPADI1PADI4KDM4EKMT2A
SCHEMBL18576499 0.68 POLB (0.47) POLBKMT2ACYP2D6TSHREPHX1
SCHEMBL17005077 0.68 CHRM1 (0.43) POLBPADI1PADI4KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680202-B2 MULTIDIMENSIONAL ARRAY OF REACTION VESSELS WITH LIQUID REACTION MIXTURES AND A SEPARATE ARRAY OF ?TEABAGS? HAVING FIXED REACTANTS LOCATED THEREON ADVANCED AUTOMATIONS, L.L.C. 2004-01-20 US disclosed
US-20030186445-A1 Method for concurrent and sequential multi-step reactions for producing a plurality of different chemical compounds ADVANCED AUTOMATIONS, L.L.C. 2003-10-02 US disclosed
US-6537504-B1 Dynamic matrix system ADVANCED AUTOMATION, L.L.C. 2003-03-25 US disclosed