Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7750679 | 0.99 | SSTR4 (0.55) | SSTR4HPGDOPRM1OPRL1SCN9A | |
| SCHEMBL7314168 | 0.96 | SSTR4 (0.54) | SSTR4HPGDOPRM1OPRL1SCN9A | |
| Hydrochloric Acid SCHEMBL7751607 | 0.94 | SSTR4 (0.53) | SSTR4HPGDOPRM1OPRL1SCN9A | |
| SCHEMBL7304625 | 0.93 | SSTR4 (0.53) | SSTR4HPGDOPRM1OPRL1SCN9A | |
| Hydrochloric Acid SCHEMBL7745884 | 0.92 | SSTR4 (0.52) | SSTR4HPGDOPRM1OPRL1SCN9A | |
| SCHEMBL4006087 | 0.86 | SSTR4 (0.54) | SSTR4HPGDOPRM1OPRL1SCN9A | |
| SCHEMBL4007365 | 0.86 | SSTR4 (0.54) | SSTR4HPGDOPRM1OPRL1SCN9A | |
| SCHEMBL29541999 | 0.82 | SSTR4 (0.55) | SSTR4OPRM1OPRL1SCN9ALMNA | |
| SCHEMBL8368922 | 0.82 | SSTR4 (0.42) | SSTR4LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL4005570 | 0.82 | SSTR4 (0.49) | SSTR4HPGDOPRM1OPRL1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673928-A1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI (FR) | 1995-09-27 | — | — | EP | disclosed |