Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.52 |
| ▸ | RXRB | P28702 | 5/20 | 0.52 |
| ▸ | RXRG | P48443 | 5/20 | 0.52 |
| ▸ | RARA | P10276 | 3/20 | 0.52 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | RARG | P13631 | 3/20 | 0.52 |
| ▸ | HNF4A | P41235 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838441 | 1.00 | RXRA (0.52) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6838439 | 1.00 | RXRA (0.52) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6840585 | 0.92 | RXRA (0.50) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6840587 | 0.92 | RXRA (0.50) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6840582 | 0.92 | RXRA (0.50) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6834187 | 0.90 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6834182 | 0.90 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6834184 | 0.90 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6840748 | 0.90 | RXRA (0.53) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6840752 | 0.90 | RXRA (0.53) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759547-B1 | REDUCES SERUM GLUCOSE AND SERUM TRIGLYCERIDE LEVELS IN DIABETIC MAMMALS WITHOUT THE UNDESIRABLE PROPERTIES OF REDUCING SERUM THYROXINE LEVELS AND TRANSIENTLY RAISING TRIGLYCERIDE LEVELS | ALLERGAN, INC. | 2004-07-06 | — | — | US | disclosed |