SCHEMBL6838474

SCHEMBL6838474

O=C(O)[C@H](O)C[C@H](O)CO

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TET2 Q6N021 6/20 0.40
KDM4A O75164 2/20 0.40
KDM4C Q9H3R0 2/20 0.40
KDM2A Q9Y2K7 2/20 0.40
TET3 O43151 2/20 0.40
PGK1 P00558 1/20 0.39
PGK2 P07205 1/20 0.39
TET1 Q8NFU7 1/20 0.37
PDE4A P27815 1/20 0.37
SLC1A1 P43005 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.35
THRB P10828 1/20 0.35
GPR84 Q9NQS5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059956 1.00 OR51E2 (0.60) OR51E2SMN1; SMN2LMNAALDH1A1TET2
SCHEMBL5902879 1.00 OR51E2 (0.60) OR51E2SMN1; SMN2LMNAALDH1A1TET2
SCHEMBL6838468 1.00 OR51E2 (0.60) OR51E2SMN1; SMN2LMNAALDH1A1TET2
SCHEMBL6839516 1.00 OR51E2 (0.60) OR51E2SMN1; SMN2LMNAALDH1A1TET2
SCHEMBL6838473 1.00 OR51E2 (0.60) OR51E2SMN1; SMN2LMNAALDH1A1TET2
SCHEMBL16600632 0.95 OR51E2 (0.55) OR51E2SMN1; SMN2LMNAALDH1A1TET2
Ethylene Glycol SCHEMBL251841 0.95 OR51E2 (0.55) OR51E2SMN1; SMN2LMNAALDH1A1TET2
Phosphoric Acid SCHEMBL28960961 0.93 OR51E2 (0.52) OR51E2SMN1; SMN2LMNAALDH1A1TET2
SCHEMBL7538335 0.80 OR51E2 (0.63) OR51E2SMN1; SMN2TET2KDM4AKDM4C
Glycerin SCHEMBL18763119 0.80 OR51E2 (0.82) OR51E2SMN1; SMN2LMNAALDH1A1TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115094016-B Recombinant escherichia coli knocked out glucose-6-phosphate isomerase gene and application thereof in production of 1,2,4-butanetriol 山东大学 2024-02-23 CN claimed
US-4853084-A Method for controlling alkaline pulping process ALEN RAIMO (FI) 1989-08-01 US claimed
CN-119876337-A High-throughput screening method of 2-keto-3-deoxy-D-xylonate dehydratase mutant library and application of mutant in biosynthesis of alpha-ketoglutarate 青岛农业大学 2025-04-25 CN disclosed
CN-119876337-A High-throughput screening method of 2-keto-3-deoxy-D-xylonate dehydratase mutant library and application of mutant in biosynthesis of alpha-ketoglutarate 青岛农业大学 2025-04-25 CN disclosed
CN-116240232-B Construction method of Weimberg xylose metabolism pathway in acetobacter xylosojae 天津科技大学 2024-11-29 CN disclosed
US-20240392329-A1 MICROORGANISMS AND METHODS FOR THE PRODUCTION OF OXYGENATED COMPOUNDS FROM HEXOSES BRASKEM S.A. (BR) 2024-11-28 US disclosed
US-12006526-B2 Microorganisms and methods for the production of oxygenated compounds from hexoses BRASKEM S.A. (BR) 2024-06-11 US disclosed
CN-114540395-B Construction method of xylose utilization metabolism in Shewanella 天津大学(青岛)海洋工程研究院有限公司 2023-06-27 CN disclosed
CN-116240232-A Construction method of Weinberg xylose metabolism pathway in acetobacter xylosoxidans 天津科技大学 2023-06-09 CN disclosed
US-20230119263-A1 Pseudomonas mutant strains with enhanced xylose and galactose utilization UNITED STATES DEPARTMENT OF ENERGY 2023-04-20 US disclosed
US-11286490-B2 Formation of alkenes through enzymatic dehydration of alkanols BRASKEM S.A. (BR) 2022-03-29 US disclosed
US-20200283806-A1 MICROORGANISMS AND METHODS FOR THE PRODUCTION OF OXYGENATED COMPOUNDS FROM HEXOSES BRASKEM S.A. (BR) 2020-09-10 US disclosed
US-20200048662-A1 MICROORGANISMS AND METHODS FOR THE CO-PRODUCTION OF ETHYLENE GLYCOL AND ISOBUTENE BRASKEM SA (BR) 2020-02-13 US disclosed
EP-3426789-A1 MICROORGANISMS AND METHODS FOR THE CO-PRODUCTION OF ETHYLENE GLYCOL AND THREE CARBON COMPOUNDS Braskem S.A. (BR) 2019-01-16 EP disclosed
US-20180179558-A1 MICROORGANISMS AND METHODS FOR THE CO-PRODUCTION OF ETHYLENE GLYCOL AND THREE CARBON COMPOUNDS BRASKEM S.A. (BR) 2018-06-28 US disclosed
US-20170260551-A1 MICROORGANISMS AND METHODS FOR THE CO-PRODUCTION OF ETHYLENE GLYCOL AND THREE CARBON COMPOUNDS BRASKEM S.A. (BR) 2017-09-14 US disclosed
WO-2017156166-A1 MICROORGANISMS AND METHODS FOR THE CO-PRODUCTION OF ETHYLENE GLYCOL AND THREE CARBON COMPOUNDS BRASKEM S.A. (BR) 2017-09-14 WO disclosed
US-9546385-B2 Genetically modified clostridium thermocellum engineered to ferment xylose ENCHI CORPORATION (US) 2017-01-17 US disclosed
US-20140370561-A1 GENETICALLY MODIFIED CLOSTRIDIUM THERMOCELLUM ENGINEERED TO FERMENT XYLOSE MASCOMA CORPORATION (US) 2014-12-18 US disclosed
US-20040254368-A1 Production of aldoses MITSUI CHEMICALS, INC. (JP) 2004-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040254368-A1 Production of aldoses ALDOA, ADH1C, AKR1C1 OR51E2 2750/4885SMN1; SMN2 2135/4885LMNA 2588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.