⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2181044 | 0.69 | — | — | |
| SCHEMBL5863104 | 0.64 | — | — | |
| SCHEMBL6917809 | 0.64 | — | — | |
| SCHEMBL5717884 | 0.63 | TSHR (0.30) | — | |
| SCHEMBL27682353 | 0.62 | — | — | |
| SCHEMBL5912862 | 0.62 | — | — | |
| SCHEMBL2077091 | 0.62 | KAT2B (0.41) | — | |
| SCHEMBL21013859 | 0.62 | POLB (0.34) | — | |
| SCHEMBL5717982 | 0.62 | CA12 (0.31) | — | |
| SCHEMBL14735589 | 0.61 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831174-B2 | Nucleosides | SHIRE BIOCHEM INC. (CA) | 2004-12-14 | — | — | US | disclosed |
| EP-0674634-B1 | PROCESS FOR PREPARING SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | IAF BIOCHEM INT (CA) | 2003-04-16 | — | — | EP | disclosed |
| US-20010041797-A1 | Processes for preparing substituted 1, 3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 2001-11-15 | — | — | US | disclosed |
| US-6175008-B1 | VIRICIDES FROM REACTION MERCAPTOALDEHYDE WITH ACETOESTER AND 1,4-DITHIANE-2,5-DIOL | BIOCHEM PHARMA INC. (CA) | 2001-01-16 | — | — | US | disclosed |
| US-5684164-A | CHEMICAL INTERMEDIATES | BIOCHEM PHARMA INC. (CA) | 1997-11-04 | — | — | US | disclosed |
| US-5466806-A | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 1995-11-14 | — | — | US | disclosed |
| EP-0674634-A1 | PROCESS FOR PREPARING SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC (CA) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014802-A1 | PROCESS FOR PREPARING SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1994-07-07 | — | — | WO | disclosed |