Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839046 | 1.00 | AKR1B10 (0.49) | AKR1B10AKR1B1GPBAR1SRD5A2SRD5A1 | |
| SCHEMBL2510574 | 0.91 | AKR1B10 (0.61) | AKR1B10AKR1B1GPBAR1ABCB11LMNA | |
| SCHEMBL28731819 | 0.89 | AKR1B10 (0.47) | AKR1B10AKR1B1GPBAR1SRD5A2SRD5A1 | |
| SCHEMBL17503652 | 0.85 | AKR1B10 (0.44) | AKR1B10AKR1B1GPBAR1SRD5A2SRD5A1 | |
| SCHEMBL9574630 | 0.85 | SRD5A2 (0.68) | SRD5A2SRD5A1ABCC4ABCB11LMNA | |
| SCHEMBL867595 | 0.84 | AR (0.61) | GPBAR1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7193192 | 0.84 | AR (0.61) | GPBAR1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL867596 | 0.84 | AR (0.61) | GPBAR1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2281371 | 0.84 | AR (0.61) | GPBAR1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15259496 | 0.84 | AR (0.61) | GPBAR1LMNACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762193-B1 | Method of treating hair loss | SANDERS JR RICHARD J (US) | 2004-07-13 | — | — | US | disclosed |
| US-6440994-B1 | Method of treating acne | SANDERS JR RICHARD J (US) | 2002-08-27 | — | — | US | disclosed |