Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839746 | 1.00 | KDM1A (0.44) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 | |
| SCHEMBL6842234 | 0.86 | KDM1A (0.49) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 | |
| SCHEMBL6835604 | 0.86 | KDM1A (0.49) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 | |
| SCHEMBL6839741 | 0.82 | F10 (0.46) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 | |
| SCHEMBL6839740 | 0.82 | F10 (0.46) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 | |
| SCHEMBL6835561 | 0.80 | F10 (0.44) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 | |
| SCHEMBL6842250 | 0.79 | KDM1A (0.47) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6839770 | 0.79 | KDM1A (0.46) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 | |
| SCHEMBL6839698 | 0.76 | KDM1A (0.44) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 | |
| SCHEMBL6842249 | 0.76 | F10 (0.45) | KDM1AMAOBF10SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082563-A1 | Phenyl derivatives 3 | MERCK PATENT GMBH (DE) | 2004-04-29 | — | — | US | claimed |
| EP-1368341-A1 | PHENYL DERIVATIVES 3 | MERCK PATENT GmbH (DE) | 2003-12-10 | — | — | EP | claimed |
| WO-2002074765-A1 | PHENYL DERIVATIVES 3 | MERCK PATENT GMBH (DE) | 2002-09-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082563-A1 | Phenyl derivatives 3 | F2, F11, F12 | KDM1A 452/4885MAOB 435/4885F10 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.