Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809470 | 0.90 | HSPA5 (0.47) | HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A | |
| SCHEMBL30443103 | 0.86 | HSPA5 (0.35) | HSPA5CYP2C19SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL17471441 | 0.83 | ESR1 (0.42) | HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A | |
| SCHEMBL27900463 | 0.83 | MAPK1 (0.36) | HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A | |
| SCHEMBL11775715 | 0.81 | KLF10 (0.41) | HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A | |
| SCHEMBL14510169 | 0.81 | HSPA5 (0.50) | HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A | |
| SCHEMBL3812708 | 0.81 | HSPA5 (0.59) | HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A | |
| SCHEMBL29975834 | 0.81 | HSPA5 (0.59) | HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A | |
| SCHEMBL27365490 | 0.81 | IDH1 (0.44) | HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A | |
| SCHEMBL1160345 | 0.80 | SMN1; SMN2 (0.41) | CYP2C19CYP2C9SMN1; SMN2HIF1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288231-A1 | RAW-MATERIAL COMPOSITIONS FOR RESIN FOR OPTICAL PART, RESIN FOR OPTICAL PART, AND OPTICAL PART | IDEMITSU KOSAN CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |