Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840681 | 1.00 | SLC22A1 (0.35) | SLC22A1OPRM1SMN1; SMN2ALDH1A1OPRD1 | |
| SCHEMBL6841376 | 0.88 | — | — | |
| SCHEMBL6841561 | 0.76 | FFAR3 (0.33) | — | |
| SCHEMBL14838831 | 0.73 | SLC22A1 (0.40) | SLC22A1OPRM1SMN1; SMN2ALDH1A1OPRD1 | |
| SCHEMBL27188028 | 0.72 | SLC22A1 (0.37) | SLC22A1OPRM1SMN1; SMN2ALDH1A1OPRD1 | |
| SCHEMBL9782049 | 0.71 | ALDH1A1 (0.41) | SLC22A1OPRM1SMN1; SMN2ALDH1A1OPRD1 | |
| SCHEMBL29275505 | 0.69 | SLC22A1 (0.37) | SLC22A1OPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL8950840 | 0.68 | SMN1; SMN2 (0.40) | SLC22A1OPRM1SMN1; SMN2ALDH1A1OPRD1 | |
| SCHEMBL20995886 | 0.67 | SMN1; SMN2 (0.39) | SLC22A1OPRM1SMN1; SMN2ALDH1A1OPRD1 | |
| SCHEMBL27800390 | 0.66 | SMN1; SMN2 (0.38) | SLC22A1OPRM1SMN1; SMN2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167351-A1 | Method for preparing (1R,4S)-2-azabicyclo[2.2.1]hept-5-ene-3-one derivatives | BERNEGGER-EGLI CHRISTINE (CH) | 2004-08-26 | — | — | US | claimed |
| US-20040167351-A1 | Method for preparing (1R,4S)-2-azabicyclo[2.2.1]hept-5-ene-3-one derivatives | BERNEGGER-EGLI CHRISTINE (CH) | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167351-A1 | Method for preparing (1R,4S)-2-azabicyclo[2.2.1]hept-5-ene-3-one derivatives | APEH, CYP51A1, CYP8B1 | SLC22A1 3567/4885OPRM1 3316/4885SMN1; SMN2 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.