Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617411 | 0.68 | MAPT (0.57) | CYP1A2HTR2BKDM4EGSTP1ALDH1A1 | |
| SCHEMBL15043446 | 0.67 | CYP1A2 (0.43) | ESR1ESR2CYP1A2HTR2CHTR2B | |
| SCHEMBL15043443 | 0.67 | KDM1A (0.45) | ESR1ESR2CYP1A2HTR2CHTR2B | |
| SCHEMBL24516525 | 0.66 | SLC6A4 (0.46) | HTR2CHTR2BKDM4EMMP13HSP90AA1 | |
| SCHEMBL30658773 | 0.66 | POLB (0.67) | ESR1ESR2CYP1A2HTR2CHTR2B | |
| SCHEMBL24516008 | 0.66 | ESR1 (0.43) | ESR1ESR2KDM4EMMP13CES2 | |
| SCHEMBL28201245 | 0.65 | CYP1A2 (0.41) | CYP1A2HTR2CHTR2BKDM4EHDAC4 | |
| SCHEMBL22862133 | 0.64 | CNR1 (0.33) | ESR1ESR2KDM1AACHE | |
| SCHEMBL18025750 | 0.62 | PDE4A (0.51) | HTR2CHTR2BKDM4EMMP13SLC6A2 | |
| SCHEMBL10297368 | 0.62 | MAPT (0.36) | CYP1A2HTR2BKDM4EHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759367-B2 | COMPRISING THERMOSENSITIVE ELEMENT AND SUPPORT, THE THERMOSENSITIVE ELEMENT CONTAINING A SUBSTANTIALLY LIGHT-INSENSITIVE ORGANIC SILVER SALT, A 3,4-DIHYDROXYBENZENE COMPOUND, A BINDER | AGFA-GEVAERT (BE) | 2004-07-06 | — | — | US | disclosed |