Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL27750698 | 0.95 | LMNA (0.50) | LMNAALOX15HSD17B10TP53TSHR | |
| Acrylic Acid SCHEMBL28129892 | 0.84 | LMNA (0.43) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL2273825 | 0.83 | — | — | |
| Acrylic Acid SCHEMBL29502206 | 0.82 | LMNA (0.71) | LMNAALOX15HSD17B10TP53TSHR | |
| Acrylic Acid SCHEMBL30431258 | 0.82 | LMNA (0.71) | LMNAALOX15HSD17B10TP53TSHR | |
| Acrylic Acid SCHEMBL1147986 | 0.82 | — | — | |
| Acrylic Acid SCHEMBL6557843 | 0.82 | LMNA (0.71) | LMNAALOX15HSD17B10TP53TSHR | |
| Acrylic Acid SCHEMBL27615806 | 0.82 | LMNA (0.71) | LMNAALOX15HSD17B10TP53TSHR | |
| Acrylic Acid SCHEMBL1399454 | 0.82 | LMNA (0.42) | LMNAALOX15HSD17B10TP53TSHR | |
| Acrylic Acid SCHEMBL1399457 | 0.82 | LMNA (0.42) | LMNAALOX15HSD17B10TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267708-B1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INT LTD (GB) | 2025-07-02 | — | — | EP | disclosed |
| US-12281203-B2 | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2025-04-22 | — | — | US | disclosed |
| US-20240309155-A1 | Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-09-19 | — | — | US | disclosed |
| EP-4267708-A1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | Infineum International Limited (GB) | 2023-11-01 | — | — | EP | disclosed |
| CN-116981758-A | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | 英菲诺姆国际有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022136384-A1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INTERNATIONAL LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |
| CN-108024920-A | Include the liquid cosmetic composition and lip processing method of high non-volatile oil content | 莱雅公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-101846672-A | Encoding detection method based on polymer microsphere change | UNIV TIANJIN | 2010-09-29 | — | — | CN | disclosed |
| US-20040019146-A1 | Elastomeric polyurethane fiber with high heat-set efficiency | INVISTA NORTH AMERICA S.A.R.L. (F/K/A ARTEVA NORTH AMERICA S.A.R.L.) | 2004-01-29 | — | — | US | disclosed |
| EP-1356144-A1 | ELASTOMERIC POLYURETHANE FIBER WITH HIGH HEAT-SET EFFICIENCY | DuPont-Toray Co. Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002050349-A1 | ELASTOMERIC POLYURETHANE FIBER WITH HIGH HEAT-SET EFFICIENCY | DUPONT-TORAY COMPANY, LTD (JP) | 2002-06-27 | — | — | WO | disclosed |
| US-4463778-A | Sausage casing formed from regenerated cellulose with an internal vinyl acetate coating | TEEPAK, INC. (US) | 1984-08-07 | — | — | US | disclosed |