Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.84 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.84 |
| ▸ | MET | P08581 | 3/20 | 0.84 |
| ▸ | PDE4A | P27815 | 3/20 | 0.84 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.84 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.84 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842338 | 0.95 | PDE4B (0.78) | PDE4BPDE4DMETPDE4APDE4C | |
| SCHEMBL6842414 | 0.95 | PDE4B (0.77) | PDE4BPDE4DMETPDE4APDE4C | |
| SCHEMBL6844033 | 0.95 | PDE4B (0.77) | PDE4BPDE4DMETPDE4APDE4C | |
| SCHEMBL6842456 | 0.94 | PDE4B (0.76) | PDE4BPDE4DMETPDE4APDE4C | |
| SCHEMBL6842569 | 0.92 | PDE4A (0.73) | PDE4BPDE4DMETPDE4APDE4C | |
| SCHEMBL6842681 | 0.92 | MET (1.00) | PDE4BPDE4DMETPDE4APDE4C | |
| SCHEMBL6844051 | 0.91 | PDE4B (0.70) | PDE4BPDE4DMETPDE4APDE4C | |
| SCHEMBL6842391 | 0.90 | PDE4B (0.70) | PDE4BPDE4DMETPDE4APDE4C | |
| SCHEMBL6842541 | 0.89 | PDE4B (0.69) | PDE4BPDE4DMETPDE4APDE4C | |
| SCHEMBL6841945 | 0.89 | PDE4B (0.69) | PDE4BPDE4DMETPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235845-A1 | Use of phosphodiesterase iv inhibitors | MERCK PATENT GESSELSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-11-25 | — | — | US | claimed |
| US-20040235845-A1 | Use of phosphodiesterase iv inhibitors | MERCK PATENT GESSELSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235845-A1 | Use of phosphodiesterase iv inhibitors | PDE4A, PDE3A, PDE3B | PDE4B 4/4885PDE4D 12/4885MET 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.