Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 6/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 5/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 5/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568130 | 0.79 | CCR1 (0.38) | MEN1LMNAMAPK1KMT2APDE2A | |
| SCHEMBL2065632 | 0.78 | NAPRT (0.41) | GRM5AKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL4943891 | 0.73 | NPC1 (0.42) | MEN1LMNAKMT2APDE2A | |
| SCHEMBL2183698 | 0.71 | AKR1C3 (0.44) | AKR1C3AKR1C2MEN1LMNAMAPK1 | |
| SCHEMBL26685092 | 0.71 | KMT2A (0.43) | SMARCA2SMARCA4MEN1LMNAKMT2A | |
| SCHEMBL27334484 | 0.71 | RECQL (0.37) | SMARCA2SMARCA4AKR1C3AKR1C2ROCK2 | |
| SCHEMBL12541474 | 0.71 | SMN1; SMN2 (0.42) | MEN1LMNAMAPK1KMT2AAR | |
| SCHEMBL2865570 | 0.71 | PREP (0.48) | GRM5KDM4CMEN1LMNAMAPK1 | |
| SCHEMBL30953476 | 0.71 | NPC1 (0.43) | SMARCA2SMARCA4KDM4CAKR1C3AKR1C2 | |
| SCHEMBL2459503 | 0.70 | CPN1 (0.45) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814871-B1 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-03-02 | — | — | EP | disclosed |