SCHEMBL2865570

SCHEMBL2865570

C[C@H](NC(=O)c1ccnc(Cl)c1)C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PREP P48147 1/20 0.48
FAP Q12884 1/20 0.48
KMT2A Q03164 3/20 0.47
LMNA P02545 3/20 0.47
TAS1R3 Q7RTX0 2/20 0.47
TAS1R1 Q7RTX1 2/20 0.47
TAS1R2 Q8TE23 2/20 0.47
MEN1 O00255 2/20 0.47
MAPK1 P28482 1/20 0.47
FDPS P14324 1/20 0.46
HPGD P15428 1/20 0.44
GRM5 P41594 2/20 0.42
ROCK2 O75116 1/20 0.41
ROCK1 Q13464 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
KDM4C Q9H3R0 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2856403 0.85 PREP (0.50) PREPFAPKMT2ALMNATAS1R3
SCHEMBL2856039 0.85 PREP (0.50) PREPFAPKMT2ALMNATAS1R3
SCHEMBL24568629 0.85 PREP (0.50) PREPFAPKMT2ALMNATAS1R3
SCHEMBL2801067 0.84 FDPS (0.57) PREPFAPKMT2ALMNATAS1R3
SCHEMBL20908956 0.81 HPGD (0.42) KMT2ATAS1R3TAS1R1TAS1R2MEN1
SCHEMBL2851987 0.80 CTSA (0.51) KMT2ALMNAMEN1MAPK1FDPS
SCHEMBL2856574 0.79 TAS1R3 (0.47) PREPFAPKMT2ALMNATAS1R3
SCHEMBL24568251 0.79 ALDH1A1 (0.53) PREPFAPKMT2ATAS1R3TAS1R1
SCHEMBL24571395 0.79 ALDH1A1 (0.53) PREPFAPKMT2ATAS1R3TAS1R1
SCHEMBL10491673 0.79 PREP (0.46) PREPFAPKMT2ALMNATAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137376-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100137376-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100137376-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
EP-2174931-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME Sumitomo Chemical Company, Limited (JP) 2010-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137376-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME NAAA, NAT1, SAT1 PREP 617/4885FAP 4212/4885KMT2A 520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.