Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.96 |
| ▸ | MEN1 | O00255 | 2/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.96 |
| ▸ | USP2 | O75604 | 1/20 | 0.96 |
| ▸ | POLB | P06746 | 1/20 | 0.96 |
| ▸ | MAPT | P10636 | 1/20 | 0.96 |
| ▸ | HPGD | P15428 | 1/20 | 0.96 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.96 |
| ▸ | BLM | P54132 | 1/20 | 0.96 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.96 |
| ▸ | HMGCR | P04035 | 3/20 | 0.81 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.66 |
| ▸ | PPARG | P37231 | 6/20 | 0.59 |
| ▸ | PPARD | Q03181 | 6/20 | 0.59 |
| ▸ | PPARA | Q07869 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742640 | 1.00 | TDP1 (1.00) | TDP1RECQLPTPN7ALDH1A1MEN1 | |
| SCHEMBL26624753 | 1.00 | TDP1 (1.00) | TDP1RECQLPTPN7ALDH1A1MEN1 | |
| SCHEMBL11071577 | 1.00 | TDP1 (1.00) | TDP1RECQLPTPN7ALDH1A1MEN1 | |
| SCHEMBL10919883 | 1.00 | TDP1 (1.00) | TDP1RECQLPTPN7ALDH1A1MEN1 | |
| SCHEMBL10458369 | 1.00 | TDP1 (1.00) | TDP1RECQLPTPN7ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9421484 | 0.98 | TDP1 (0.96) | TDP1RECQLPTPN7ALDH1A1MEN1 | |
| SCHEMBL10456798 | 0.98 | PTPN7 (1.00) | TDP1RECQLPTPN7ALDH1A1MEN1 | |
| SCHEMBL31189059 | 0.98 | PTPN7 (1.00) | TDP1RECQLPTPN7ALDH1A1MEN1 | |
| SCHEMBL10458468 | 0.98 | PTPN7 (1.00) | TDP1RECQLPTPN7ALDH1A1MEN1 | |
| SCHEMBL68751 | 0.98 | PTPN7 (1.00) | TDP1RECQLPTPN7ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150320697-A1 | Methods For Bone Treatment By Modulating An Arachidonic Acid Metabolic or Signaling Pathway | ACCELALOX, INC. | 2015-11-12 | — | — | US | claimed |
| EP-1947942-B1 | METHODS FOR BONE TREATMENT BY MODULATING AN ARACHIDONIC ACID METABOLIC OR SIGNALING PATHWAY | ACCELALOX INC (US) | 2015-07-29 | — | — | EP | claimed |
| US-8980851-B2 | Methods for bone treatment by modulating an arachidonic acid metabolic or signaling pathway | ACCELALOX, INC. (US) | 2015-03-17 | — | — | US | claimed |
| EP-1867994-B1 | Ligand for G-protein coupled receptor GPR72 and uses thereof | EUROSCREEN SA (BE) | 2012-09-26 | — | — | EP | claimed |
| US-20110124717-A1 | Methods for Bone Treatment by Modulating an Arachidonic Acid Metabolic or Signaling Pathway | ACCELALOX, INC. (US) | 2011-05-26 | — | — | US | claimed |
| US-7829535-B2 | for promoting osteogenesis to accelerate or enhance bone fracture healing, treat bone defects, and enhance bone formation are disclosed. The methods modulate an arachidonic acid metabolic or signaling pathway in general, and, in particular, utilize 5-lipoxygenase inhibitors. | ACCELALOX, INC. (US) | 2010-11-09 | — | — | US | claimed |
| US-20080280826-A1 | for promoting osteogenesis to accelerate or enhance bone fracture healing, treat bone defects, and enhance bone formation are disclosed. The methods modulate an arachidonic acid metabolic or signaling pathway in general, and, in particular, utilize 5-lipoxygenase inhibitors. | ACCELALOX, INC. (US) | 2008-11-13 | — | — | US | claimed |
| US-20080274124-A1 | Ligand for G-protein coupled receptor GPR72 and uses thereof | EUROSCREEN S. A. | 2008-11-06 | — | — | US | claimed |
| EP-1947942-A2 | METHODS FOR BONE TREATMENT BY MODULATING AN ARACHIDONIC ACID METABOLIC OR SIGNALING PATHWAY | Accelalox, Inc. (US) | 2008-07-30 | — | — | EP | claimed |
| EP-1867994-A2 | Ligand for G-protein coupled receptor GPR72 and uses thereof | Euroscreen S.A. (BE) | 2007-12-19 | — | — | EP | claimed |
| US-5310959-A | Reacting 1-decyne with 1,4-dihalo-2-butyne using a strong base and then reacting with 5-hexynoic acid; reacting with an amine in the presense of carbonyldiimidazole to amidate | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1994-05-10 | — | — | US | claimed |
| EP-0420707-B1 | Compositions to be used to reduce hair-loss and to induce and stimulate its growth, containing derivatives of 2-aminopyrimidine 3-oxide and new compounds derived from 2-aminopyrimidine 3-oxide | OREAL (FR) | 1993-12-15 | — | — | EP | claimed |
| EP-0303871-B1 | OXADIAZOLOPYRIMIDINONES, THEIR PREPARATION AND THEIR COSMETIC AND DERMOPHARMACEUTICAL USE | L'OREAL (FR) | 1992-12-09 | — | — | EP | claimed |
| US-5132106-A | Treatment of baldness | L'OREAL (FR) | 1992-07-21 | — | — | US | claimed |
| EP-0304665-B1 | 2,4,6-TRIAMINO-N-3-OXIDE-PYRIMIDINE UREA DERIVATIVES, THEIR PREPARATION AND THEIR COSMETICAL AND DERMOPHARMACEUTICAL USE | L'OREAL (FR) | 1992-04-15 | — | — | EP | claimed |
| US-5034387-A | Applying to skins for hair growth and skin disorders | L'OREAL (FR) | 1991-07-23 | — | — | US | claimed |
| US-4973474-A | 2,4-diaminopyrimidine 3-oxide derivatives and their use for the treatment and prevention of hair loss | L'OREAL (FR) | 1990-11-27 | — | — | US | claimed |
| EP-0396251-A2 | Use of fatty acids for the treatment of diseases associated with cytokines | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 1990-11-07 | — | — | EP | claimed |
| US-4190669-A | EICOSA-POLY-YNOIC ACID OR ESTER | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1980-02-26 | — | — | US | claimed |
| US-4181725-A | BROMOPHENACYL BROMIDE, TOCOPHEROL, MEPACRINE, (HYDROXY)CHLOROQUINE, DIBUCAINE, TETRACAINE, LIDOCAINE, BUTACAINE, PROCAINE, EDTA | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1980-01-01 | — | — | US | claimed |