Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HMGCR | P04035 | 3/20 | 0.78 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | PPARD | Q03181 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458468 | 1.00 | PTPN7 (1.00) | PTPN7TDP1ALDH1A1RECQLMEN1 | |
| SCHEMBL31189059 | 1.00 | PTPN7 (1.00) | PTPN7TDP1ALDH1A1RECQLMEN1 | |
| SCHEMBL10456798 | 1.00 | PTPN7 (1.00) | PTPN7TDP1ALDH1A1RECQLMEN1 | |
| SCHEMBL10458369 | 0.98 | TDP1 (1.00) | PTPN7TDP1ALDH1A1RECQLMEN1 | |
| SCHEMBL28742640 | 0.98 | TDP1 (1.00) | PTPN7TDP1ALDH1A1RECQLMEN1 | |
| SCHEMBL11071577 | 0.98 | TDP1 (1.00) | PTPN7TDP1ALDH1A1RECQLMEN1 | |
| SCHEMBL26624753 | 0.98 | TDP1 (1.00) | PTPN7TDP1ALDH1A1RECQLMEN1 | |
| SCHEMBL10919883 | 0.98 | TDP1 (1.00) | PTPN7TDP1ALDH1A1RECQLMEN1 | |
| SCHEMBL68425 | 0.98 | TDP1 (1.00) | PTPN7TDP1ALDH1A1RECQLMEN1 | |
| Hydrochloric Acid SCHEMBL9421484 | 0.96 | TDP1 (0.96) | PTPN7TDP1ALDH1A1RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 741 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4744663-A2 | SKIN COMPOSITION | Eaderm Co., Ltd. (JP) | 2026-05-20 | — | — | EP | claimed |
| CN-118079006-A | Skin composition | 国立大学法人东京医科齿科大学 | 2024-05-28 | — | — | CN | claimed |
| US-20220331389-A1 | SKIN COMPOSITION | EADERM CO., LTD. (JP) | 2022-10-20 | — | — | US | claimed |
| EP-3978020-A1 | SKIN COMPOSITION | National University Corporation Tokyo Medical and Dental University (JP) | 2022-04-06 | — | — | EP | claimed |
| EP-3878947-A2 | MATURATION OF MAMMALIAN HEPATOCYTES | Takara Bio Europe AB (SE) | 2021-09-15 | — | — | EP | claimed |
| US-20210189332-A1 | MATURATION OF MAMMALIAN HEPATOCYTES | TAKARA BIO EUROPE AB (SE) | 2021-06-24 | — | — | US | claimed |
| US-10913932-B2 | Maturation of mammalian hepatocytes | TAKARA BIO EUROPE AB (SE) | 2021-02-09 | — | — | US | claimed |
| US-20190024044-A1 | MATURATION OF MAMMALIAN HEPATOCYTES | TAKARA BIO EUROPE AB (SE) | 2019-01-24 | — | — | US | claimed |
| US-10105455-B2 | Fluorocoxib A loading into ROS-responsive nanoparticles | VANDERBILT UNIVERSITY (US) | 2018-10-23 | — | — | US | claimed |
| US-9945843-B2 | Methods for identifying compounds that inhibit G protein-coupled receptor (GPR84) agonist-stimulated chemotaxis | GALAPAGOS NV (BE) | 2018-04-17 | — | — | US | claimed |
| US-6060515-A | TOPICALLY APPLYING TO MAMMALIAN SKIN OR MUCOUS MEMBRANE A BARRIER DEVELOPMENT ENHANCING AMOUNT OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPARA) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-05-09 | — | — | US | claimed |
| CN-1248916-A | Use of FXR, PPAR 'alpha' and LXR 'alpha' activators to restore barrier function, promote epidermal differentiation and inhibit proliferation | UNIV CALIFORNIA (US) | 2000-03-29 | — | — | CN | claimed |
| US-6004987-A | ANTIINFLAMMATORY AGENTS FOR MAMMALS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-12-21 | — | — | US | claimed |
| WO-1998032444-A1 | USE OF FXR, PPARα AND LXRα ACTIVATORS TO RESTORE BARRIER FUNCTION, PROMOTE EPIDERMAL DIFFERENTIATION AND INHIBIT PROLIFERATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-30 | — | — | WO | claimed |
| US-5760043-A | USING 2-AMINOPYRIDINE-3-OXIDE | L'OREAL (FR) | 1998-06-02 | — | — | US | claimed |
| EP-0353123-B1 | Ureic 2,4,6-triamino-pyrimidine-3-oxide derivatives, their preparation and their cosmetical and dermapharmaceutical use | OREAL (FR) | 1994-08-24 | — | — | EP | claimed |
| EP-0279954-B1 | AMIDES OF EICOSATETRAYNOIC ACID, THEIR PHARMACEUTICAL AND COSMETIC USE, THEIR PREPARATION AND PROCESS FOR THE PREPARATION OF EICOSATETRAYNOIC ACID | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-03-17 | — | — | EP | claimed |
| US-5034387-A | Applying to skins for hair growth and skin disorders | L'OREAL (FR) | 1991-07-23 | — | — | US | claimed |
| EP-0396251-A2 | Use of fatty acids for the treatment of diseases associated with cytokines | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 1990-11-07 | — | — | EP | claimed |
| US-4181725-A | BROMOPHENACYL BROMIDE, TOCOPHEROL, MEPACRINE, (HYDROXY)CHLOROQUINE, DIBUCAINE, TETRACAINE, LIDOCAINE, BUTACAINE, PROCAINE, EDTA | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1980-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10105455-B2 | Fluorocoxib A loading into ROS-responsive nanoparticles | ROS1, CYBB, NOXO1 | PTPN7 2112/4885TDP1 3282/4885ALDH1A1 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.