Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.59 |
| ▸ | DRD2 | P14416 | 7/20 | 0.59 |
| ▸ | DRD3 | P35462 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774517 | 0.85 | DRD4 (0.64) | DRD4DRD2DRD3MEN1POLB | |
| SCHEMBL16829430 | 0.84 | KDM4E (0.64) | GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3174309 | 0.83 | DRD4 (0.62) | DRD4DRD2DRD3MEN1POLB | |
| SCHEMBL22123024 | 0.82 | ALDH1A1 (0.67) | DRD4DRD2DRD3POLBGAA | |
| SCHEMBL2228237 | 0.81 | ALDH1A1 (0.66) | DRD4DRD2DRD3MEN1POLB | |
| SCHEMBL16617729 | 0.81 | DRD4 (0.63) | DRD4DRD2DRD3MEN1POLB | |
| SCHEMBL885731 | 0.81 | DRD4 (0.59) | DRD4DRD2DRD3MEN1POLB | |
| SCHEMBL13531644 | 0.78 | DRD4 (0.57) | DRD4DRD2DRD3MEN1POLB | |
| SCHEMBL22122851 | 0.78 | SMN1; SMN2 (0.63) | POLBKMT2ASIGMAR1OPRD1GAA | |
| SCHEMBL22124598 | 0.78 | SMN1; SMN2 (0.62) | DRD4DRD2DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013082756-A1 | PHOSPHATE TRANSPORT INHIBITORS II | LEO PHARMA A/S (DK) | 2013-06-13 | — | — | WO | claimed |
| WO-2013082751-A1 | PHOSPHATE TRANSPORT INHIBITORS I | LEO PHARMA A/S (DK) | 2013-06-13 | — | — | WO | claimed |
| CN-107982266-A | Carbamate compounds and its preparation and application | 阿比德治疗公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-104159581-B | Carbamate compounds and methods of making and using the same | 阿比德治疗公司 | 2017-09-01 | — | — | CN | disclosed |
| US-6680318-B2 | FOR THERAPY OF PAIN, GASTROINTESTINAL DISORDERS, SPINAL INJURIES | ASTRAZENECA AB (SE) | 2004-01-20 | — | — | US | disclosed |