Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acetamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL27777446 | 0.87 | LMNA (0.43) | LMNACA2CA1TSHRALDH1A1 | |
| Acetamidine SCHEMBL6287555 | 0.85 | BLM (0.43) | BLMLMNAALOX15PMP22CA2 | |
| Acetic Acid SCHEMBL11016035 | 0.84 | FFAR3 (0.47) | LMNACA2CA1TSHRALDH1A1 | |
| SCHEMBL975520 | 0.84 | TDP1 (0.60) | BLMLMNAALOX15PMP22CA2 | |
| Hydroxyamine SCHEMBL27900806 | 0.83 | — | — | |
| Hydrazine SCHEMBL679587 | 0.83 | — | — | |
| Methylamine SCHEMBL143865 | 0.83 | — | — | |
| SCHEMBL27346657 | 0.83 | TSHR (0.50) | CA2CA1TSHRALDH1A1USP2 | |
| SCHEMBL5991 | 0.83 | — | — | |
| SCHEMBL27308161 | 0.83 | TSHR (0.50) | CA2CA1TSHRALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6764613-B2 | FOR USE IN BLEACHING AND CLEANING | MID-AMERICA COMMERCIALIZATION CORPORATION | 2004-07-20 | — | — | US | disclosed |
| US-6235218-B1 | REACTING HETEROCYCLIC AMINE WITH MONOALDEHYDE OR DIALDEHYDE AND HYDROGEN CYANIDE OR ALKALI METAL CYANIDE IN AQUEOUS MEDIUM, QUATERNIZING AMINE WITH ALKYLATING AGENT AT PH CONTROLLED TO PREVENT FORMATION OF PROTONATED INTERMEDIATE | THE CLOROX COMPANY | 2001-05-22 | — | — | US | disclosed |
| US-6183665-B1 | BLEACHING | THE CLOROX COMPANY | 2001-02-06 | — | — | US | disclosed |