Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828694 | 0.75 | MAPT (0.49) | MAPTALDH1A1RECQLSLC7A5PKM | |
| SCHEMBL11120452 | 0.75 | TNF (0.39) | MAPTALDH1A1RECQLSLC7A5PKM | |
| SCHEMBL23120097 | 0.74 | SLC7A5 (0.50) | MAPTALDH1A1RECQLSLC7A5PKM | |
| SCHEMBL28738543 | 0.74 | SLC7A5 (0.50) | MAPTALDH1A1RECQLSLC7A5PKM | |
| SCHEMBL23120674 | 0.74 | MAPT (0.51) | MAPTALDH1A1RECQLSLC7A5PKM | |
| SCHEMBL1162358 | 0.73 | MAPT (0.47) | MAPTALDH1A1RECQLSLC7A5PKM | |
| SCHEMBL22807019 | 0.72 | MAPT (0.67) | MAPTALDH1A1RECQLSLC7A5PKM | |
| SCHEMBL29550977 | 0.72 | MAPT (0.67) | MAPTALDH1A1RECQLSLC7A5PKM | |
| SCHEMBL120341 | 0.72 | MAPT (0.67) | MAPTALDH1A1RECQLSLC7A5PKM | |
| SCHEMBL1520299 | 0.71 | MAPT (0.48) | MAPTALDH1A1RECQLSLC7A5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259256-A1 | Methods of unnatural amino acid incorporation in mammalian cells | NEURION PHARMACEUTICALS | 2004-12-23 | — | — | US | disclosed |
| WO-2004085463-A2 | METHODS OF UNNATURAL AMINO ACID INCORPORATION IN PROTEINS IN MAMMALIAN CELLS | NEURION PHARMACEUTICALS (US) | 2004-10-07 | — | — | WO | disclosed |