SCHEMBL23120674

SCHEMBL23120674

NC(Cc1c(Br)n(Br)c2ccccc12)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.51
▸ ALDH1A1 P00352 1/20 0.51
▸ RECQL P46063 1/20 0.51
▸ SLC7A5 Q01650 3/20 0.46
▸ ALPI P09923 1/20 0.46
▸ PKM P14618 1/20 0.46
▸ PTGS1 P23219 1/20 0.46
▸ XIAP P98170 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ MPO P05164 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ BLM P54132 1/20 0.46
▸ PMP22 Q01453 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ HIF1A Q16665 1/20 0.46
▸ NOS3 P29474 2/20 0.40
▸ NOS1 P29475 2/20 0.40
▸ NOS2 P35228 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8651825 0.76 MAPT (0.46) MAPTALDH1A1RECQLSLC7A5ALPI
SCHEMBL1060620 0.75 MAPT (0.67) MAPTALDH1A1RECQLSLC7A5ALPI
SCHEMBL828694 0.75 MAPT (0.49) MAPTALDH1A1RECQLSLC7A5ALPI
SCHEMBL29550970 0.75 MAPT (0.67) MAPTALDH1A1RECQLSLC7A5ALPI
SCHEMBL28738543 0.74 SLC7A5 (0.50) MAPTALDH1A1RECQLSLC7A5ALPI
SCHEMBL6843793 0.74 MAPT (0.48) MAPTALDH1A1RECQLSLC7A5ALPI
SCHEMBL23120097 0.74 SLC7A5 (0.50) MAPTALDH1A1RECQLSLC7A5ALPI
SCHEMBL1162358 0.73 MAPT (0.47) MAPTALDH1A1RECQLSLC7A5ALPI
SCHEMBL1520299 0.71 MAPT (0.48) MAPTALDH1A1RECQLSLC7A5ALPI
SCHEMBL1996403 0.71 MAPT (0.48) MAPTALDH1A1RECQLSLC7A5ALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250354108-A1 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS UNIV DANMARKS TEKNISKE (DK) 2025-11-20 — — US disclosed
EP-4526426-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS Danmarks Tekniske Universitet (DK) 2025-03-26 — — EP disclosed
WO-2023222879-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-23 — — WO disclosed
US-20220403428-A1 YEAST CELLS AND METHODS FOR PRODUCTION OF TRYPTOPHAN DERIVATIVES DANMARKS TEKNISKE UNIVERSITET (DK) 2022-12-22 — — US disclosed
EP-4031671-A1 YEAST CELLS AND METHODS FOR PRODUCTION OF TRYPTOPHAN DERIVATIVES Danmarks Tekniske Universitet (DK) 2022-07-27 — — EP disclosed
WO-2021052989-A1 YEAST CELLS AND METHODS FOR PRODUCTION OF TRYPTOPHAN DERIVATIVES DANMARKS TEKNISKE UNIVERSITET (DK) 2021-03-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250354108-A1 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS INMT, KARS1, MIA3 MAPT 3008/4885ALDH1A1 781/4885RECQL 2935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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