Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762892 | 0.79 | MCL1 (0.50) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL143643 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL10771650 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL5168254 | 0.79 | MCL1 (0.50) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL143642 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL679854 | 0.79 | MCL1 (0.50) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL23458002 | 0.74 | AKR1C3 (0.73) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL60657 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL598776 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL6433811 | 0.74 | AKR1C3 (0.73) | ALDH1A1TSHRAKR1C3FBP1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209849-A1 | Use of effectors of the central cholinergic nervous system for treatment of delirium | SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT (AT) | 2004-10-21 | — | — | US | disclosed |