Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.47 |
| ▸ | WNT3A | P56704 | 4/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21274689 | 0.87 | BACE1 (0.50) | HDAC1HDAC8CAPN1HDAC3HDAC4 | |
| SCHEMBL6263512 | 0.85 | HDAC1 (0.56) | HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL4883079 | 0.84 | HDAC1 (0.55) | HDAC1HDAC8CTNNB1WNT3AUSP2 | |
| SCHEMBL9225433 | 0.83 | HDAC1 (0.54) | HDAC1HDAC8CTNNB1WNT3AF2 | |
| SCHEMBL30006673 | 0.83 | HDAC1 (0.54) | HDAC1HDAC8CTNNB1WNT3AF2 | |
| SCHEMBL14820597 | 0.82 | HDAC1 (0.71) | HDAC1HDAC8CTNNB1WNT3AF2 | |
| SCHEMBL8666600 | 0.80 | HDAC1 (0.55) | HDAC1HDAC8CTNNB1WNT3AF2 | |
| SCHEMBL6303056 | 0.80 | HDAC1 (0.51) | HDAC1HDAC8CTNNB1WNT3AUSP2 | |
| SCHEMBL15901671 | 0.80 | HDAC1 (0.54) | HDAC1HDAC8CTNNB1WNT3AMAOB | |
| SCHEMBL28325361 | 0.79 | HDAC1 (0.60) | HDAC1HDAC8CTNNB1WNT3AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279782-A | Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases | 詹森生物科技公司 | 2022-11-01 | — | — | CN | disclosed |
| EP-1330457-B1 | CYCLOPENTA[B][1,4] DIAZEPINO[6,7,1-HI]INDOLES AS 5HT2C ANTAGONISTS | WYETH CORP (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |
| CN-1208413-A | Gonadotropin releasing hormone antagonists | MERCK & CO INC (US) | 1999-02-17 | — | — | CN | disclosed |