Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.47 |
| ▸ | WNT3A | P56704 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30233681 | 0.87 | MAOA (0.51) | HDAC1HDAC8MAOACYP1A2CYP3A4 | |
| SCHEMBL6263512 | 0.85 | HDAC1 (0.56) | HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL6844115 | 0.84 | HDAC1 (0.55) | HDAC1HDAC8MAOACTNNB1WNT3A | |
| SCHEMBL6303056 | 0.83 | HDAC1 (0.51) | HDAC1HDAC8MAOACTNNB1WNT3A | |
| SCHEMBL15901671 | 0.83 | HDAC1 (0.54) | HDAC1HDAC8MAOACYP1A2CYP3A4 | |
| SCHEMBL14155863 | 0.82 | HDAC1 (0.71) | HDAC1HDAC8MAOACYP1A2CYP3A4 | |
| SCHEMBL8666600 | 0.80 | HDAC1 (0.55) | HDAC1HDAC8MAOACYP1A2CYP3A4 | |
| SCHEMBL14833860 | 0.80 | HDAC1 (0.51) | HDAC1HDAC8MAOACYP1A2CYP3A4 | |
| SCHEMBL28325361 | 0.79 | HDAC1 (0.60) | HDAC1HDAC8MAOACYP1A2SLC6A3 | |
| Benzylacetone SCHEMBL28244875 | 0.78 | ALDH1A1 (0.64) | HDAC8KDM4ESLC6A2SLC6A3CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016972-A | Preparation method of vilazodone as well as hydrochloride and intermediate thereof | SHANGHAI HECHEN PHARMA ENGINEERING CO LTD | 2014-09-03 | — | — | CN | claimed |
| CN-104016972-A | Preparation method of vilazodone as well as hydrochloride and intermediate thereof | SHANGHAI HECHEN PHARMA ENGINEERING CO LTD | 2014-09-03 | — | — | CN | disclosed |
| US-20080267942-A1 | BENZAZEPIN-2(1H)-ONE DERIVATIVES | PFIZER LIMITED (GB) | 2008-10-30 | — | — | US | disclosed |
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | PFIZER LIMITED (GB) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | ADRB2, ADRB1, ADRA2C | HDAC1 1929/4885HDAC8 1507/4885MAOA 1568/4885 |
| US-20080267942-A1 | BENZAZEPIN-2(1H)-ONE DERIVATIVES | ADRB2, ADRB1, ADRA2C | HDAC1 1362/4885HDAC8 1565/4885MAOA 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.