SCHEMBL6844440

SCHEMBL6844440

CN1CCCC1CCN1C(=O)c2cccc(NC(=O)c3sccc3Cl)c2C1=O

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 19/20 0.49
ACHE P22303 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4304803 0.83 ACHE (0.49) CHRM3ACHE
SCHEMBL6667667 0.78 ACHE (0.46) CHRM3ACHE
SCHEMBL4302308 0.68 ACHE (0.56) ACHE
SCHEMBL4309831 0.68 ACHE (0.61) ACHE
SCHEMBL6698295 0.67 ACHE (0.53) ACHE
SCHEMBL4314194 0.67 F10 (0.55) CHRM3
SCHEMBL4309214 0.67 CHRM3 (0.43) CHRM3
SCHEMBL4312080 0.66 ACHE (0.56) ACHE
Iodide SCHEMBL4318141 0.66 ACHE (0.52) ACHE
SCHEMBL4306482 0.66 CHRM3 (0.44) CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040215019-A1 Substituted isoindoles and the e use thereof BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2004-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040215019-A1 Substituted isoindoles and the e use thereof F2, F12, F5 CHRM3 3206/4885ACHE 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.