Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.47 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL2362456 | 0.96 | CA1 (0.64) | CA1CA4LMNASLC34A1FAHD1 | |
| Phosphoric Acid SCHEMBL2362457 | 0.96 | CA1 (0.64) | CA1CA4LMNASLC34A1FAHD1 | |
| Phosphoric Acid SCHEMBL1039724 | 0.92 | CA1 (0.69) | CA1CA4LMNASLC34A1FAHD1 | |
| Phosphoric Acid SCHEMBL31657790 | 0.92 | CA1 (0.61) | CA1CA4LMNASLC34A1TSHR | |
| Phosphoric Acid SCHEMBL10839221 | 0.92 | CA1 (0.61) | CA1CA4LMNASLC34A1TSHR | |
| Phosphoric Acid SCHEMBL17978034 | 0.92 | CA1 (0.61) | CA1CA4LMNASLC34A1TSHR | |
| Phosphoric Acid SCHEMBL10838736 | 0.92 | CA1 (0.61) | CA1CA4LMNASLC34A1TSHR | |
| Phosphoric Acid SCHEMBL5509352 | 0.89 | CA1 (0.57) | CA1CA4LMNASLC34A1TSHR | |
| Phosphoric Acid SCHEMBL31536919 | 0.89 | CA1 (0.64) | CA1CA4LMNASLC34A1FAHD1 | |
| Phosphoric Acid SCHEMBL5806288 | 0.89 | CA1 (0.57) | CA1CA4LMNASLC34A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770455-B1 | PREPARATION, USE AND MEDICAMENTS CONTAINING RIBONUCLEOTIDE POLYPEPTIDES OR THEIR MOLECULAR-BIOLOGICAL EQUIVALENT STRUCTURES AND/OR PARTS AND/OR DERIVATIVES | Fraunhofer—Gesellschaft zur Forderung der Angewandten Forschung E.V. (DE) | 2004-08-03 | — | — | US | disclosed |
| US-6087123-A | NUCLEIC ACID PROTEIN; FOR THE NON-MITOGEN CONTROL OF CELLULAR RESPONSE; FOR INDUCTION OF A NEOVASCULARISATION OF TISSUES; WOUND HEALING AGENTS; ANTITUMOR AGENTS | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2000-07-11 | — | — | US | disclosed |