Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | TAF1 | P21675 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2340384 | 0.85 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL2340390 | 0.85 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL29755289 | 0.82 | BRD4 (0.39) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL2050140 | 0.82 | BRD4 (0.40) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL2050138 | 0.82 | BRD4 (0.40) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL6840372 | 0.81 | BRD4 (0.39) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL2027438 | 0.79 | KMT2A (0.40) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL2027436 | 0.79 | KMT2A (0.40) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL2052918 | 0.78 | MEN1 (0.36) | KMT2AMEN1PSEN1PSEN2APH1B | |
| SCHEMBL2052915 | 0.78 | MEN1 (0.36) | KMT2AMEN1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079118-A1 | PTERIDINONES AS INHIBITORS OF POLO-LIKE KINASE | ELAN PHARMACEUTICALS, INC (US) | 2011-06-30 | — | — | WO | disclosed |