Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5588763 | 0.82 | SELL (0.42) | DUSP3PTPN5PTPN11CTDSP1DPP4 | |
| SCHEMBL22097577 | 0.79 | TTR (0.44) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL1649000 | 0.79 | CA12 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL433284 | 0.76 | KDM4E (0.42) | DUSP3PTPN5PTPN11CTDSP1TTR | |
| SCHEMBL31006010 | 0.75 | CA12 (0.50) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL6494516 | 0.75 | CA12 (0.50) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL6844843 | 0.75 | HSD17B10 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5756953 | 0.74 | CA12 (0.40) | DUSP3PTPN5PTPN11CTDSP1CA12 | |
| SCHEMBL433360 | 0.74 | TSHR (0.42) | DUSP3PTPN5PTPN11CTDSP1CA12 | |
| SCHEMBL5693093 | 0.73 | CA12 (0.46) | DUSP3PTPN5PTPN11CTDSP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |