Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19674785 | 0.85 | CD44 (0.35) | CYP3A4SMN1; SMN2MAPK1HTTCD44 | |
| SCHEMBL11154303 | 0.85 | TDP1 (0.39) | LMNACYP3A4SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL559000 | 0.81 | CD44 (0.37) | LMNACYP3A4SMN1; SMN2HTTCD44 | |
| SCHEMBL3001668 | 0.81 | LMNA (0.32) | LMNAMAPTKMT2AHPGD | |
| SCHEMBL22165264 | 0.81 | HPGD (0.43) | LMNACYP3A4SMN1; SMN2MAPTHTT | |
| SCHEMBL29331735 | 0.81 | APP (0.32) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11294968 | 0.81 | MAPT (0.38) | LMNACYP3A4MAPTMAPK1ALDH1A1 | |
| SCHEMBL19964756 | 0.81 | CD44 (0.48) | LMNACYP3A4SMN1; SMN2CD44ALDH1A1 | |
| SCHEMBL11156180 | 0.79 | LMNA (0.31) | LMNAKMT2A | |
| SCHEMBL20457096 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028576-B | Production process of 3, 5-dichloro-2, 6-dimethyl-4-hydroxypyridine | 广西金源生物化工实业有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-115028576-A | Production process of 3, 5-dichloro-2, 6-dimethyl-4-hydroxypyridine | 广西金源生物化工实业有限公司 | 2022-09-09 | — | — | CN | disclosed |
| EP-2691095-B1 | IMIDAZOLYL AMIDE COMPOUNDS AND USES RELATED THERETO | UNIV EMORY (US) | 2017-07-05 | — | — | EP | disclosed |
| US-9365523-B2 | Imidazolyl amide compounds and uses related thereto | EMORY UNIVERSITY (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160101104-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2016-04-14 | — | — | US | disclosed |
| US-20150342935-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2015-12-03 | — | — | US | disclosed |
| US-20140221377-A1 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | BRISTOL MYERS SQUIBB CO (US) | 2014-08-07 | — | — | US | disclosed |
| US-20140080828-A1 | IMIDAZOLYL AMIDE COMPOUNDS AND USES RELATED THERETO | CHILDREN'S HEATLHCARE OF ATLANTA, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20130131064-A1 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2011053292-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-05 | — | — | WO | disclosed |
| US-4620033-A | CATALYST OF NICKEL COMPOUND, IODIDE COMPOUND AND PROMOTER OF TIN COMPOUND AND LITHIUM COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1986-10-28 | — | — | US | disclosed |
| US-4544511-A | CATALYST CONTAINING NICKEL, HALIDES AND ORGANIC NITROGEN COMPOUND;COCATALYST OF METAL COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-10-01 | — | — | US | disclosed |
| EP-0035860-B1 | PROCESS FOR PRODUCING ETHYLIDENE DIACETATE AND/OR ACETALDEHYDE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1984-03-14 | — | — | EP | disclosed |
| EP-0048174-B1 | PROCESS FOR PRODUCING VINYL ACETATE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1984-02-22 | — | — | EP | disclosed |
| EP-0065817-A1 | Process for producing carboxylic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-12-01 | — | — | EP | disclosed |
| EP-0055622-A1 | Process for producing acetic anhydride | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-07-07 | — | — | EP | disclosed |
| EP-0048174-A1 | Process for producing vinyl acetate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-03-24 | — | — | EP | disclosed |
| EP-0035860-A2 | Process for producing ethylidene diacetate and/or acetaldehyde | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1981-09-16 | — | — | EP | disclosed |
| US-3938259-A | Process for continuous drying of chemical products by milling-fluidisation | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080828-A1 | IMIDAZOLYL AMIDE COMPOUNDS AND USES RELATED THERETO | TPMT, PNP, MTAP | LMNA 3734/4885CYP3A4 249/4885SMN1; SMN2 2371/4885 |
| US-20140221377-A1 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | CHRNA7, CHRNA5, CHRNA6 | LMNA 2215/4885CYP3A4 2815/4885SMN1; SMN2 813/4885 |
| US-20130131064-A1 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | CHRNA7, CHRNA5, CHRNA6 | LMNA 2215/4885CYP3A4 2815/4885SMN1; SMN2 813/4885 |
| US-20160101104-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | CHRNA7, CHRNA5, CHRNA6 | LMNA 2215/4885CYP3A4 2815/4885SMN1; SMN2 813/4885 |
| US-20150342935-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | CHRNA7, CHRNA5, CHRNA6 | LMNA 2215/4885CYP3A4 2815/4885SMN1; SMN2 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.