Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850899 | 0.86 | CHRNA7 (0.41) | CHRNA7HTR3A | |
| SCHEMBL6844468 | 0.85 | CHRNA7 (0.45) | CHRNA7HTR3A | |
| SCHEMBL6850918 | 0.84 | CHRNA7 (0.43) | CHRNA7HTR3A | |
| SCHEMBL6849590 | 0.84 | CHRNA7 (0.43) | CHRNA7HTR3A | |
| SCHEMBL6848456 | 0.84 | CHRNA7 (0.44) | CHRNA7HTR3A | |
| SCHEMBL6850910 | 0.84 | CHRNA7 (0.44) | CHRNA7HTR3A | |
| SCHEMBL6844533 | 0.83 | CHRNA7 (0.44) | CHRNA7HTR3A | |
| SCHEMBL6849264 | 0.83 | CHRNA7 (0.42) | CHRNA7HTR3A | |
| SCHEMBL6851281 | 0.83 | CHRNA7 (0.41) | CHRNA7HTR3APDE9A | |
| SCHEMBL6848604 | 0.82 | CHRNA7 (0.41) | CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432707-A1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2004-06-30 | — | — | EP | claimed |
| WO-2003029252-A1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-10 | — | — | WO | claimed |
| EP-1432707-A1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003029252-A1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-10 | — | — | WO | disclosed |