Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25626247 | 0.87 | ALDH1A1 (0.33) | TDP1ALDH1A1TSHR | |
| SCHEMBL25698114 | 0.83 | TDP1 (0.33) | TDP1 | |
| SCHEMBL13562812 | 0.82 | — | — | |
| SCHEMBL9967232 | 0.81 | TDP1 (0.32) | TDP1 | |
| SCHEMBL14067340 | 0.81 | TDP1 (0.32) | TDP1 | |
| SCHEMBL22926680 | 0.78 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL10050367 | 0.76 | — | — | |
| SCHEMBL11256849 | 0.76 | — | — | |
| SCHEMBL14067086 | 0.75 | — | — | |
| SCHEMBL19047606 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069884-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2017090756-A1 | NOVEL BIPHENYL COMPOUND OR SALT THEREOF | 大鵬薬品工業株式会社 | 2017-06-01 | — | — | WO | disclosed |
| EP-3101015-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | EA Pharma Co., Ltd. (JP) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015175707-A1 | HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2015-11-19 | — | — | WO | disclosed |
| WO-2013152063-A1 | NAPHTHYRIDINONE DERIVATIVES AS INHIBITORS OF CYTOMEGALOVIRUS DNA POLYMERASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-10 | — | — | WO | disclosed |
| WO-2011115938-A1 | SPIRO-TETRACYCLIC RING COMPOUNDS AS BETA - SECRETASE MODULATORS | AMGEN INC. (US) | 2011-09-22 | — | — | WO | disclosed |
| EP-1661568-B1 | Compounds effecting Glucokinase | ASTRAZENECA AB (SE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1597242-B1 | HIV INHIBITING 1,2,4-TRIAZINES | JANSSEN PHARMACEUTICA NV (BE) | 2008-07-23 | — | — | EP | disclosed |