Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732937 | 1.00 | CA1 (0.39) | CA1CA2CA7CA9PDE10A | |
| SCHEMBL2463060 | 0.85 | SMN1; SMN2 (0.40) | HTR1A | |
| SCHEMBL29676737 | 0.85 | SMN1; SMN2 (0.40) | HTR1A | |
| SCHEMBL30587348 | 0.79 | PTPRC (0.32) | — | |
| SCHEMBL16406236 | 0.77 | SMN1; SMN2 (0.36) | GNRHR | |
| SCHEMBL28542865 | 0.77 | KCNN4 (0.39) | CA1CA2CA7CA9PDE10A | |
| SCHEMBL18323806 | 0.76 | SMN1; SMN2 (0.43) | HTR1AHTR2AHTR2B | |
| SCHEMBL648482 | 0.75 | BCHE (0.37) | — | |
| SCHEMBL26968808 | 0.75 | PDE10A (0.32) | PDE10AHTR1A | |
| SCHEMBL20143725 | 0.75 | BRD4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116965-A1 | ORGANOMETALLIC COMPOUNDS | UMICORE AG & CO. KG (DE) | 2024-04-11 | — | — | US | disclosed |
| EP-4294814-A1 | METAL COMPLEXES HAVING 4-H, 6-H OR 8-H DIHYDROAZULENYL LIGANDS AND USE THEREOF | Umicore AG & Co. KG (DE) | 2023-12-27 | — | — | EP | disclosed |
| WO-2022175111-A1 | METAL COMPLEXES HAVING 4-H, 6-H OR 8-H DIHYDROAZULENYL LIGANDS AND USE THEREOF | UMICORE AG & CO. KG (DE) | 2022-08-25 | — | — | WO | disclosed |
| EP-4047003-A1 | METAL COMPLEXES WITH 4-H-, 6-H- OR 8-H-DIHYDROAZULENYL LIGANDS AND THEIR USE | UMICORE AG & Co. KG (DE) | 2022-08-24 | — | — | EP | disclosed |
| US-11117889-B1 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| CN-105492075-B | Inhibitors of viral replication, their preparation method and their therapeutical uses | HIVIH公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-110023287-A | Pesticidally active heterocyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-106317129-B | amino ferrocene derivative and organic light emitting diode | 郑建鸿 | 2019-06-14 | — | — | CN | disclosed |
| CN-109790149-A | PHENOXYTRIAZOLES | 豪夫迈·罗氏有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-104903320-B | Nitrogen-containing heterocycle compound or its salt | 富士胶片株式会社 | 2018-11-13 | — | — | CN | disclosed |
| CN-106317129-A | Amino ferrocene derivative and organic light emitting diode | 郑建鸿 | 2017-01-11 | — | — | CN | disclosed |
| WO-2011115928-A1 | AMINO -DIHYDROOXAZINE AND AMINO - DIHYDROTHIAZINE SPIRO COMPOUNDS AS BETA - SECRETASE MODULATORS AND THEIR MEDICAL USE | AMGEN INC. (US) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11117889-B1 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | CA1 4622/4885CA2 4617/4885CA7 3754/4885 |
| US-20240116965-A1 | ORGANOMETALLIC COMPOUNDS | DDT, PPOX, PDCD2L | CA1 3884/4885CA2 3103/4885CA7 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.