Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743971 | 0.85 | SLC6A4 (0.50) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL7179104 | 0.80 | SLC6A4 (0.45) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL4374880 | 0.70 | SLC6A2 (0.66) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL6743948 | 0.69 | SLC6A4 (0.52) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL6741554 | 0.69 | SLC6A4 (0.52) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL6741500 | 0.68 | SLC6A4 (0.54) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL6743000 | 0.67 | SLC6A4 (0.50) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL6742994 | 0.67 | SLC6A2 (0.52) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL7172155 | 0.67 | SLC6A4 (0.60) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL6744430 | 0.66 | SLC6A4 (0.48) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322593-B1 | O-SUBSTITUTED 6-METHYL-TRAMADOL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2004-07-28 | — | — | EP | disclosed |