Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 17/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 16/20 | 0.60 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374880 | 0.94 | SLC6A2 (0.66) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL6744715 | 0.91 | OPRM1 (0.64) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL6741527 | 0.91 | OPRM1 (0.64) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL6784987 | 0.91 | OPRM1 (0.64) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| Hydrochloric Acid SCHEMBL6780749 | 0.90 | OPRM1 (0.62) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| Hydrochloric Acid SCHEMBL7186390 | 0.90 | OPRM1 (0.62) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| Hydrochloric Acid SCHEMBL6780745 | 0.90 | OPRM1 (0.62) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL6743948 | 0.84 | SLC6A4 (0.52) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL6741554 | 0.84 | SLC6A4 (0.52) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL6742994 | 0.83 | SLC6A2 (0.52) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322593-A1 | O-SUBSTITUTED 6-METHYL-TRAMADOL DERIVATIVES | Grünenthal GmbH (DE) | 2003-07-02 | — | — | EP | claimed |
| WO-2002026694-A1 | O-SUBSTITUTED 6-METHYL-TRAMADOL DERIVATIVES | Grünenthal GmbH (DE) | 2002-04-04 | — | — | WO | claimed |