Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 4/20 | 0.41 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13899096 | 0.97 | GAA (0.47) | GAAMCL1PPARGMEP1BMEP1A | |
| SCHEMBL5746078 | 0.90 | PPARG (0.53) | GAAMCL1PPARGHDAC6HDAC3 | |
| SCHEMBL5745760 | 0.90 | MCL1 (0.46) | GAAMCL1LMNASMN1; SMN2 | |
| SCHEMBL1236963 | 0.89 | SMN1; SMN2 (0.40) | GAAMEP1BMEP1AHDAC6HDAC3 | |
| SCHEMBL12888487 | 0.89 | SMN1; SMN2 (0.40) | GAAMEP1BMEP1AHDAC6HDAC3 | |
| SCHEMBL12888440 | 0.89 | SMN1; SMN2 (0.40) | GAAMEP1BMEP1AHDAC6HDAC3 | |
| SCHEMBL12888484 | 0.89 | SMN1; SMN2 (0.40) | GAAMEP1BMEP1AHDAC6HDAC3 | |
| SCHEMBL5796641 | 0.89 | GAA (0.41) | GAAMCL1PPARGHDAC6HDAC3 | |
| SCHEMBL6847051 | 0.89 | PPARG (0.43) | GAAMCL1PPARGHDAC6HDAC3 | |
| SCHEMBL1237061 | 0.88 | SMN1; SMN2 (0.40) | GAAMEP1BMEP1AHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |