Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745464 | 0.93 | GAA (0.41) | GAAHDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL6846303 | 0.89 | GAA (0.49) | GAAHDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL5746105 | 0.88 | PPARG (0.49) | GAADRD2SMN1; SMN2PPARGGFER | |
| SCHEMBL13899096 | 0.87 | GAA (0.47) | GAAHDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL6847051 | 0.85 | PPARG (0.43) | GAAHDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL5747025 | 0.84 | PPARG (0.45) | GAAHDAC6HDAC3HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL5747287 | 0.84 | PPARG (0.42) | GAAHDAC6HDAC3HDAC1HDAC7 | |
| SCHEMBL5746821 | 0.82 | LMNA (0.53) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL5746219 | 0.81 | PPARG (0.40) | GAAHDAC8SMN1; SMN2PPARGMAPT | |
| SCHEMBL5745831 | 0.81 | GAA (0.44) | GAASMN1; SMN2PPARGMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |