SCHEMBL6846436

SCHEMBL6846436

C#CC1(O[Si](CC)(CC)CC)CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6849084 1.00
SCHEMBL6137266 0.98
SCHEMBL666848 0.77
SCHEMBL8387047 0.77
SCHEMBL1420238 0.74
Bromide SCHEMBL29004090 0.69
SCHEMBL26965454 0.69
SCHEMBL3330004 0.69 MEN1 (0.31)
SCHEMBL28797319 0.68
SCHEMBL15213283 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113150358-B Conductive fluorosilicone rubber foam composite material and preparation method and application thereof 杭州师范大学 2022-06-28 CN disclosed
CN-111138864-B Fluorine-containing oil-resistant anti-swelling silicone rubber foam material and preparation method thereof 杭州师范大学 2022-03-08 CN disclosed
CN-113150358-A Conductive fluorosilicone rubber foam composite material and preparation method and application thereof 杭州师范大学 2021-07-23 CN disclosed
CN-111138864-A Fluorine-containing oil-resistant anti-swelling silicone rubber foam material and preparation method thereof 杭州师范大学 2020-05-12 CN disclosed
US-6822112-B1 PROSTAGLANDIN D2 AGONISTS; KIDNEY, CARDIOVASCULAR, AND SLEEP DISORDERS; ANTIISCHEMIC AND HYPOTENSIVE AGENTS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2004-11-23 US disclosed
EP-0805682-B1 DERMATOLOGICAL USE OF VITAMIN D DERIVATIVES BASILEA PHARMACEUTICA AG (CH) 2004-08-11 EP disclosed
EP-1219600-A1 PROSTAGLANDIN DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD (JP) 2002-07-03 EP disclosed
US-5827883-A TOPICAL DRUG DELIVERY; SIDE EFFECT REDUCTION HOFFMANN-LA ROCHE INC. (US) 1998-10-27 US disclosed
EP-0805682-A1 DERMATOLOGICAL USE OF VITAMIN D DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1997-11-12 EP disclosed
WO-1996022776-A1 DERMATOLOGICAL USE OF VITAMIN D DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1996-08-01 WO disclosed