SCHEMBL6847155

SCHEMBL6847155

NCCC(=O)c1ccc(Cl)s1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.63
F2 P00734 1/20 0.59
DAO P14920 1/20 0.53
ALDH1A1 P00352 10/20 0.51
MAPT P10636 6/20 0.51
HPGD P15428 6/20 0.51
GAA P10253 1/20 0.51
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
NPC1 O15118 1/20 0.47
ALOX12 P18054 1/20 0.47
RAB9A P51151 1/20 0.47
HSD17B10 Q99714 1/20 0.47
POLB P06746 2/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
THRB P10828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15988636 0.88 GSK3B (0.73) GSK3BF2DAOALDH1A1MAPT
SCHEMBL17459466 0.84 GSK3B (0.68) GSK3BF2DAOALDH1A1MAPT
SCHEMBL982447 0.82 GSK3B (0.71) GSK3BF2DAOALDH1A1MAPT
Propylamine SCHEMBL10351726 0.81 GSK3B (0.59) GSK3BF2DAOALDH1A1MAPT
SCHEMBL1984819 0.81 GSK3B (0.63) GSK3BF2DAOALDH1A1MAPT
SCHEMBL11232468 0.81 GSK3B (0.63) GSK3BF2DAOALDH1A1MAPT
Propylamine SCHEMBL10352536 0.80 GSK3B (0.58) GSK3BF2DAOALDH1A1MAPT
SCHEMBL11196961 0.79 GSK3B (0.67) GSK3BF2DAOALDH1A1MAPT
SCHEMBL15988680 0.79 HPGD (0.77) GSK3BALDH1A1MAPTHPGDGAA
SCHEMBL15979701 0.78 ALDH1A1 (0.68) GSK3BF2DAOALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011055561-A1 PROTEIN CROSSLINKING INHIBITOR AND USE THEREOF 独立行政法人科学技術振興機構 (JP) 2011-05-12 WO disclosed