Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.63 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl 3-Phenylpropanoate SCHEMBL304816 | 0.93 | TDP1 (0.75) | TDP1CYP4F2CYP4A11ALOX5ABCB1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL7440447 | 0.91 | TDP1 (0.72) | TDP1CYP4F2CYP4A11ALOX5ABCB1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL311047 | 0.88 | TDP1 (0.68) | TDP1CYP4F2CYP4A11ALOX5ABCB1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL3322728 | 0.88 | CYP4F2 (0.70) | TDP1CYP4F2CYP4A11ALOX5ABCB1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL28983325 | 0.88 | TDP1 (0.68) | TDP1CYP4F2CYP4A11ALOX5ABCB1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL27762292 | 0.88 | TDP1 (0.68) | TDP1CYP4F2CYP4A11ALOX5ABCB1 | |
| SCHEMBL2773061 | 0.87 | CYP4F2 (0.68) | TDP1CYP4F2CYP4A11ALOX5ABCB1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL8614481 | 0.87 | TDP1 (0.66) | TDP1CYP4F2CYP4A11ALOX5ABCB1 | |
| SCHEMBL9858129 | 0.87 | TDP1 (0.66) | TDP1CYP4F2CYP4A11ALOX5ABCB1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL27562389 | 0.85 | CYP4F2 (0.66) | TDP1CYP4F2CYP4A11ALOX5ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747052-B2 | ANTICANCER AGENTS | CYTOVIA, INC. | 2004-06-08 | — | — | US | disclosed |
| US-20030105140-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-06-05 | — | — | US | disclosed |
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | TDP1 1563/4885CYP4F2 3030/4885CYP4A11 2265/4885 |
| US-20030105140-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | TDP1 1563/4885CYP4F2 3030/4885CYP4A11 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.